CREATING LIFE: IS IT A BLESSING OR A CALL FOR AN UNKNOWN DISASTER?

Life was formed 3.6 billion years ago. Some scientist’s are of different view. There are various models for origin of life and is a debatable issue. Religious groups take a different stand. But whatever it is, evolution of life is still a mystery. Scientists after their experiment had arrived at a conclusion that life arose from a single cell. That which has the capacity to replicate, and its progeny replicated them, and so on, with lots of genetic twists and it is carried on from generations to generations and thus we find the living beings in this world.

Imagine all this started with just a DNA (Deoxy Ribo Nuclic Acid)!

Today, every living organism – every person, plant, animal and microbe – can trace its heritage back to that first cell.

Imagine amongst this present day species, arrives some new comers and here we are not talking of some extraterrestrials. Scientists in the last couple of years have been trying to create novel forms of life. They’ve forged chemicals into synthetic DNA, the DNA into genes, genes into genomes and built the molecular machinery of completely new organisms in their lab, such type of organisms that are nothing like anything Nature has produced before. We do not know, what forms of life that would be. Will the new species succumb us or it will help us to move our life with more ease is a question, which time can only answer. If the earlier fact is true then we are into trouble. As, it would be the reason for a new disaster!

If the latter part is true, we can live a better life. The notion of creating life in the lab has plenty of detractors. Some Scientists aren’t convinced it can be done and religious leaders and environmentalists are in arm against this move. But there are also lots of advantages to it. Jay Keasling at UC Berkeley received $ 42 million from Bill Gates to create living microfactories that manufacture a powerful antimalaria agent. (Newsweek). Imagine that a microbe being created that would circulate in the blood and hunt down Cancer Cells, Imagine such type of bio devices that could conceivably have enormous advantages over traditional manufacturing processes and sources of material. Cell machinery that could operate the equivalent of multistep production lines at molecular level, fabricating complex chemical products precisely, atom by atom.  They would also work cheaply and efficiently, fed by simple safe substances like sugar. A few such types of projects are already giving us a glimpse of the power of this new field. The most extraordinary effort is to create a microbial organism that would produce a powerful antimalarial drug.

New York Times newspaper reports: ‘Such Biofabs produce made- to- order genes, the stretches of DNA that contain the instructions for living creatures.’ Sale of gene-synthesis industry are estimated at only $ 50 million a year, but they are growing rapidly. One foundry in Germany, has gone public. It says it expects sales this year to increase at least 60% , to 12.5 million euros, or about $17 billion, New York Times report.

The ability to make genes has given rise to a new subject called synthetic biology, which might lead to artificial life in very few years. Genetic Engineers extract a gene from an organism. Then they might modify it and put it in a different organism. There is certainly a behavior change in the organism. It then acts in the desired way. And once this bio device is designed and properly fabricated, the hard work becomes over – its users can instruct it to make as many copies of itself, by itself, as are needed. This Biodevices could make impossible drugs, including ones that are quite impossible to create through traditional chemistry. While there might be some other biodevices created that act as sensitive environmental biosensors, programmed to detect and degrade specific toxic organisms or  act as indicators like glow in the proximity of a biological, chemical or radioactive weapon. Anything is possible with these genetically modified organisms.

An organization is eyeing an even bigger prize: a self sustaining, highly efficient biological organism that converts sunlight directly into clean biofuel, with minimal environmental impact and zero net release of greenhouse gases (Newsweek).

Now, look at it in this way. Imagine that any of these mutated forms of biodevice doesn’t obey orders.

A species, which becomes an enemy of its own masters, it’s own Gods.

Probably, it would be a day, when humans have to wage war against that unknown species, which if wins, would lead to our extinction. Pope Benedict XVI has expressed outrage at scientists who “modify the very grammar of life as planned and willed by God.”

Some critics point out that Government should devise some regulations for saving Humans from any such mishaps.  “The result is not bioterror,” ETC Group, a technology watcher said in a report, “but BIOERROR” and we write our own annihilation story.

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Thanks and Regards,

Mr. Mainak Majumdar

Disaster Management Specialist and Consultant

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